"Aspirin Cardio": instructions for use, analogues, composition and reviews

Every year, cardiovascular diseases such as cerebral stroke, myocardial infarction, angina, take the lives of many people of different ages. Scientists from different countries are working to create drugs that can prevent the development of diseases of the heart and blood vessels, as well as reduce their symptoms. Among such drugs, the drug Aspirin Cardio, developed by the leading German company Bayer, has become particularly popular.

History of the creation of drugs

aspirin cardioThe history of the creation of the drug "Aspirin Cardio" is inextricably linked with the world famous drug "Aspirin", which is well studied and with proven effectiveness. Acetylsalicylic acid was discovered in the late 19th century at the same well-known Bayer plant and patented as a drug with analgesic and anti-inflammatory activity.And only half a century later, the new possibilities of this acid were discovered to exert an anti-agglutination effect on blood platelets. Numerous clinical studies using aspirin have shown high efficacy of this drug in the treatment of myocardial infarction and coronary heart disease. It has been proven that this drug in small doses has a better effect than the usual tablet with the norm of the active substance 500 mg. However, there was a negative effect of acetylsalicylic acid on the digestive tract, in which it can cause irritation and damage to the mucosa, which leads to its ulceration. To remove the negative effects of taking aspirin, technologists modified the composition of the drug. Tablets of the new drug were coated with a multi-layer lacquer coating with acid-resistant properties. Also reduced the dosage of the active substance. A new trade name for the drug, “Aspirin Cardio”, was invented. In Russia, the drug is also registered under this brand name and is prescribed to patients with diseases of the heart, blood vessels and hypertension.

Dosage form and composition of the drug

As well as all over the world, the medicinal form of the drug "Aspirin Cardio" is represented by round tablets, biconvex. Outside, the tablet is covered with an enteric coating of white color.

Due to the soluble coating, the drug Aspirin Cardio has a slightly different composition than its predecessor, the drug Aspirin, by Bayer. The active substance remained acetylsalicylic acid at a dosage of 100 mg and 300 mg. This is a significantly lower content of the active substance in the dosage unit than in the usual drug "Aspirin". Manufacturers use other ingredients to form tablets, but they do not have any therapeutic effect on the body. It is powdered cellulose and corn starch.

A more complex composition has a three-layer coating tablets. It consists of talc, sodium lauryl sulfate, triethyl acetate, a copolymer formed of methacrylic acid and ethyl ester of acrylic acid. Also included is an emulsifier - Tween 80. Such a complex composition of the shell allows the tablet to pass through the integral sections of the stomach, and its dissolution begins only in the intestine.

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The drug "Aspirin Cardio", analogues

As mentioned earlier, the tablets of the drug "Aspirin Cardio" are original, first patented by German manufacturers. Recently in the pharmaceutical market there are more and more similar agents, similar in composition, therapeutic effect and relative safety. The drug "Aspirin Cardio" has analogues with a protective sheath and without it. For uncoated tablets, special antacid ingredients are used, which temporarily protect the gastric mucosa from the harmful effects of acid.

Treatment of diseases of the cardiovascular system with TromboAss, Aspinat, Cardiomagnyl, Aspinat 300, Aspicor, AspinatCardio, Mikristin, Acenterin, Taspirin, Acekardol, Kolfarit "speaks of their analogy with the Aspirin Cardio." All these drugs have the same active ingredient - acetylsalicylic acid, only in different quantities. Other ingredients of the tablet may differ, but they should not affect the dynamics and kinetics of the main substance.

If the patient is faced with the question of which drug to choose: "ThromboASS" or "Aspirin Cardio", you need to know their similarities and differences.According to the international classification, both drugs belong to the group of non-steroidal anti-inflammatory drugs, the indications for use are the same, the tablets are coated with a protective coating, which indicates their safety. These two European-made drugs, only the drug "TromboASS" is Austrian, and the medicine "Aspirin Cardio" is German. The composition of the tablets there are differences in excipients, in the preparation "ThromboASS" there are more of them. Various ingredients are contained in the shells of these drugs. In addition, we should not forget that on generic counterparts prices are an order of magnitude lower than on the original tool. Therefore, the drug "ThromboASS" is considered a more affordable drug for the unprotected segments of the population, it can often be found in the pharmacy.

If there is a choice: "Cardiomagnyl" or "Aspirin Cardio", it should be noted that these analogues belong to the same classification group of nonsteroidal anti-inflammatory drugs. Only the first belongs to the group of antacid agents. The active component is the same, and the other components are different. Unlike the drug "Aspirin Cardio", the pills of the "Cardiomagnyl" means are not coated.To reduce the irritating effect, the antacid component of magnesium hydroxide was introduced into its composition, which envelops the walls of the stomach and promotes the development of mucous secretions.

But do not self-medicate, only the attending doctor must decide which drug to take, especially if there are problems with digestion.

The mechanism of action of the drug

The original drug "Aspirin Cardio" manual contains information on pharmacodynamic and pharmacokinetic features. How does this medicine affect the human body?

aspirin cardio instructionThe main active substance, acetylsalicylic acid, is capable of blocking the enzyme system responsible for the synthesis of prostaglandins, which cause inflammatory processes in cells. The analgesic and antipyretic effect of the drug is carried out by reducing the sensitivity of the cells of the nervous system, this is due to a decrease in the number of mediators of inflammatory reactions. The ability to provide anti-inflammatory, antipyretic, analgesic effect of the drug "Aspirin Cardio" is much lower than that of the simple remedy "Aspirin" with a dosage of 500 mg.

The second main feature of the acid is to prevent platelets from sticking together with each other or with the wall of blood vessels. It is carried out due to inhibition of the production of thromboxanes in the blood cells responsible for coagulability. The drug "Aspirin Cardio" has a long-lasting effect, the use of its single dose helps to reduce platelet aggregation for a whole week.

Acetylsalicylic acid as part of the tablet enhances the dissolution of fibrin clots in the blood plasma, while reducing the concentration of coagulation factors dependent on vitamin K. This explains the ability of the drug to have a fibrinolytic effect.

The acid from the tablet is released into the cavity of the duodenum 12, this is facilitated by the alkaline reaction of the intestine, in which the dissolution of the protective membrane takes place. Then the active substance is completely absorbed into the blood and is spread to the diseased organs. Excreted by the kidneys in the form of acetylsalicylic acid metabolites.

What diseases are treated with this tool?

Before taking the drug "Aspirin Cardio" instructions for use of this medication must be read by the patient. It contains all the necessary information.

aspirin cardio instructions for useAn important section of the instructions for the tool "Aspirin Cardio" - "Indications for use", which states that this drug is used for all diseases associated with excessive blood clots. It is prescribed as a blood thinning agent for the treatment and prevention of coronary heart disease in its various forms, myocardial infarction in diabetes mellitus, increased pressure, overweight, stable and unstable stenocardia. Medicine "Aspirin" helps to prevent the occurrence of heart attacks and strokes, prevents the formation of blood clots in blood vessels that already contain cholesterol plaques on their walls. For prophylactic purposes, it is used in surgical interventions to avoid blood clots.

The drug Aspirin Cardio is multifunctional, its indications extend to the nervous system when cerebral blood flow is disturbed, ischemic states of the brain. Received widespread use as a prophylactic venous thrombophlebitis of the extremities, with blockage of the artery of the lung or his heart attacks.All of the above conditions are accompanied by increased blood viscosity caused by adhesion of platelet cells.

Rules of taking the drug

The method of use of a drug depends on its characteristics. Thus, the drug "Aspirin Cardio" should be drunk before meals so that the food does not interfere with the absorption of the active substance in the intestine. It is very important to swallow the tablet as a whole, so as not to damage its protective shell. Only at the first signs of unstable angina pill is recommended to grind, so that the drug is better absorbed and quickly acted. Wash down with plenty of water.

If the patient is prescribed the means "Aspirin Cardio", how to take it in various conditions, prompts the section of the instruction "Methods of application". This section details the dosage of the drug for each indication.

aspirin cardio analogsAvailable in the packaging of the drug "Aspirin Cardio" instruction usually sets the daily dosage, which is taken at one time. As a preventive measure to prevent the acute development of the infarction state of the heart muscle, it is 100 mg or 300 mg, then alternate receiving and non-receiving days.

In order to prevent the development of recurrent infarction conditions, various types of stenocardia, strokes, thromboembolism, after surgical operations on the veins, daily dosages of 100-300 mg are used. After a myocardial infarction within a month, the daily dosage is 200-300 mg.

For prophylactic purposes, the drug is prescribed for long-term use, it is necessary to periodically test for blood clotting in order to control the action of acetylsalicylic acid. The doctor should cancel the drug after examining the results of the blood test.

Little about side effects

Occasionally, patients who take Aspirin Cardio products receive feedback on various changes in their health status. The organs of the gastrointestinal tract, the hematopoietic, nervous, and urinary systems are the most affected by acetylsalicylic acid. Allergic reactions may occur.

Means "Aspirin Cardio", reviews of people on its effect on the digestive system confirm this, can cause adverse reactions in the form of nausea, vomiting, increased acidity, pain in the abdomen. Sometimes there may be ulceration of the mucous in the stomach or duodenum, liver dysfunction.There are isolated cases of bleeding in the gastrointestinal tract.aspirin cardio contraindications

The risk of hemorrhage is associated with the diluting effect of the drug on blood cells, which manifest as bleeding in the nose, gums, urinary and genital organs, hematomas on the skin. As a result of long-term blood loss, iron deficiency in the body develops, leading to a decrease in hemoglobin levels.

The human body reacts differently to the drug "Aspirin Cardio", instructions for use include a list of allergic reactions observed in various systems. This may be asthma in the bronchi, swelling of the mucous membranes of the nose, eyes, allergic rhinitis, manifestations on the skin in the form of itching, rashes. In the worst cases, the state of shock develops.

There are cases when this drug can cause headache, fainting, hearing impairment, which indicates its effect on the nervous system.

The kidneys may also suffer from the action of acetylsalicylic acid, as a result of which their insufficiency develops.

Are there overdose cases?

If the patient has not read the instructions attached to the Aspirin Cardio, the reviews of overdose with this drug can be followed immediately.So, in case of exceeding the therapeutic dose of this medicine, the body becomes poisoned with salicylates, which the liver simply cannot neutralize quickly.

Distinguish between primary poisoning, when an overestimated dose was taken in a single dose, and chronic, which occurs with prolonged use of a large amount of the drug, it does not appear immediately.

Chronic poisoning is difficult to diagnose, but acute poisoning with a large dose of acetylsalicylic acid is characterized by dizziness, hearing loss, sweating, vomiting reflex, electrolyte and acid-base imbalances. All these manifestations disappear when the dose of the drug in the blood decreases to the desired limits.

In severe cases, respiratory disorders, cardiac activity, increased pressure, renal failure, mucosal bleeding can occur.

When the first signs of poisoning appear, a person should be immediately hospitalized in a hospital, where he is obliged to wash his stomach. Depending on the condition, the patient is given activated charcoal, forced urination is stimulated withalkalinization of the urine, which leads to greater removal of acid, can be assigned to clean the blood by hemodialysis.

Who is the drug contraindicated?

Not all patients, doctors prescribe the drug "Aspirin Cardio", reviews of patients about the suspicious symptoms that appear also serve as a reason to cancel this drug. There are diseases in which you can not take this medicine. These may be allergic reactions to the active component of Aspirin Cardio or other drugs from its group, reduced platelet count in the blood, asthma attacks (for acetylsalicylic acid), low hereditary blood clotting, increased bleeding, ulceration of the gastrointestinal mucosa, and liver. in a state of cirrhosis, renal failure.

Has the drug "Aspirin Cardio" contraindications for pregnant women in the first and third trimesters, but in the second it is used only in special cases as prescribed by a doctor. Acetylsalicylic acid penetrates through the placenta into the blood of the fetus and can cause various disturbances in the development of the embryo, which indicates its toxicity.In the later periods, taking the drug can cause a decrease in contractions, abundant blood loss during and after childbirth, and cerebral hemorrhages in a child.

It does not interfere with caution in the use of this drug in the formation of stones in the kidneys, bladder or ducts, asthmatic conditions, the deposition of uric acid salts in various tissues and its high content in the blood, alcohol abuse, hepatitis, after suffering a gastrointestinal ulcer. Admission is contraindicated in children under 18 years.

High degree of safety and efficacy of the drug

aspirin cardio testimonyIn most cases, the drug is accompanied by good tolerance and high rates of therapeutic action. After all, the tablets underwent numerous preclinical tests on animals, and only after the obtained positive results were clinical trials conducted on humans.

The merit of the manufacturers of the drug "Aspirin Cardio" is the development of a protective shell that does not allow the tablet to dissolve in the gastric juice, and thus protects the mucosa from the irritating action of acetylsalicylic acid.This greatly reduces the occurrence of systemic side effects from the digestive system, compared with the methods of unprotected aspirin tablets. Unwanted symptoms are more local.

Another advantage of the drug "Aspirin Cardio" is its small dosage, which is less likely to cause side effects to the mucous membranes. So, a dose of 100 mg of acetylsalicylic acid with its long-term use can reduce the synthesis of platelet enzyme, and at the same time does not inhibit the formation of prostaglandin mediators. That is why small dosages are recommended to be prescribed for diseases of the cardiovascular system, accompanied by an increased risk of blood clots.

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