Antifungal cream "Clotrimazole": instructions for use

Cream "Clotrimazole" is an antifungal topical agent intended exclusively for outdoor use. This drug belongs to the pharmacological group of imidazole derivatives.

general information

Antibacterial cream called "Clotrimazole" has a wide range of beneficial effects, which covers almost all pathogenic fungi, provoking the development of various kinds of infections. For example, this remedy is very effective against dermatophytes, streptococci, actinomycetes, erythrasma, staphylococci and blastomycosis.

Clotrimazole Cream

In addition, the cream "Clotrimazole" well helps in the fight against mold fungi, pathogens of multi-colored lichen, dimorphic fungi and other bacteria of gram-positive and gram-negative type. When used in high concentrations, this drug acts mainly fungicide, in small concentrations - fungistatically.

Features pharmacological action

clotrimazole cream for thrush

The mechanism of action of such antifungal agents as cream "Clotrimazole", is to inhibit the formation of ergosterol, which is the main element of the structure of the cell wall of pathogenic microorganisms. The absence of this substance causes significant changes in the properties of fungi. The increased permeability of the membrane provokes the lysis of the pathogenic cell, which greatly facilitates the accumulation inside the microbe of methyl typeterol type 14 L, which are precursors in the formation of ergosterol. In addition, this antifungal and antibacterial cream inhibits the activity of an enzyme such as peroxidase, which greatly facilitates the accumulation of hydrogen peroxide in a pathogenic cell and contributes to its subsequent destruction. At the same time, the manufacturer emphasizes that in addition to the pronounced antimycotic effect of the drug, Clotrimazole produces an anti-amebic and antitrihomonad action.

Antifungal Pharmacology

As regards the pharmacology of this drug, after directly applying to the infected surface of the skin the cream covers it with a small protective layer, not allowing the moisture to evaporate.At this time, the active active ingredient that is present in the composition of the drug penetrates into the middle and surface layers, providing an antibacterial and antifungal effect. In this case, the drug is not able to have a general effect on the patient’s body and is not absorbed into the circulatory system. The latter is directly related to the fact that this antimycotic agent does not penetrate well through the mucous membranes and skin.

Description of the composition and form of release

clotrimazole cream instruction

Antifungal and antibacterial cream "Clotrimazole" is produced in the form of a homogeneous mass of white or white-yellow color, which includes clotrimazole as an active element. Substances such as cetostearyl alcohol, methyl parahydroxybenzoate, emulsion wax, glycerol, polysorbate 80, propyl parahydroxybenzoate and propylene glycol act as auxiliary components. In addition, small amounts of castor oil, monoglycerides and distilled water are present.

Area of ​​use of antifungal agent

Clotrimazole Cream

It is recommended to use Clotrimazole antifungal ointment for the treatment of bacterial and fungal and fungal skin infections, foot mycosis and skin folds,provoked by pathogenic microbes sensitive to clotrimazole and accompanied by pronounced dry skin. For example, this antibacterial agent is well suited for the treatment of diseases caused by dermatophytes. In case of inguinal athlete's disease, trichomoniasis, smooth skin trichophytia, balanitis and microsporia, it is also indicated to use the drug "Clotrimazole" Cream instruction advises to apply for candidiasis (surface) and other diseases that are accompanied by desquamation and increased dryness. Including this ointment is often prescribed for fungal paronychia, erythrasma, microsporia, interdigital fungal erosion, and pityriasis. Mycoses, complicated by the so-called secondary pyoderma, effectively eliminate the antibacterial drug Clotrimazole. Cream for thrush female patients also helps very well, for a relatively short time eliminating the unpleasant symptoms of the disease.

Application features

clotrimazole cream for thrush

This antibacterial agent should be used only externally by applying a thin layer directly on the affected area of ​​the mucous membrane or skin. The drug must be very carefully rubbed until completely absorbed.In this case, this procedure should be carried out two to three times a day. With regard to a single dosage of the drug, then you should rub into the skin a column of antibacterial cream "Clotrimazole" no longer than five to seven millimeters. The duration of treatment is usually about four weeks. However, even at the end of the course and with the complete disappearance of the painful symptoms, doctors often recommend extending therapy for another ten to fourteen days to prevent a recurrence of the existing ailment.

List of contraindications

clotrimazole cream instruction

Experts strictly do not recommend using this antifungal and antibacterial agent to all those people who suffer from increased individual intolerance to clotrimazole or any other components that are present in the composition of the described agent. In addition, this antimycotic ointment is not always necessary to use in inflammatory weeping processes. In such cases, a mandatory prior consultation with a doctor is required. In addition, do not use the anti-bacterial cream "Clotrimazole" during the first trimester of pregnancy.With great care apply this antifungal drug for a variety of disorders in the liver. In addition, under medical supervision using this tool in the second and third trimesters of pregnancy and while breastfeeding a newborn.

List of side effects

The use of antifungal cream "Clotrimazole" in certain categories of patients can provoke the appearance of edema and paresthesia, peeling and irritation of the skin. Experts point out that there may be local reactions such as burning and redness. There is also a risk of blistering and erythematous rash. In patients with hypersensitivity, various kinds of allergic reactions may occur. For example, urticaria or itching. In the case of intravaginal use of this antibacterial drug, vaginal discharge, gastralgia, headaches and intercurrent cystitis may begin. Among other things, some female patients complain of burning, flushing, itching, swelling of the mucous membranes, frequent urination and pain during intercourse.At the same time, the partner may have a slight tingling. If side effects appear, you should consult with your doctor about the advisability of further use of the drug.

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